Pycharm 2017.3 Python 3.6.4 OpenCV 3.4.1 Anaconda 64-bit Py3.5 Pip 9.0.3 Pypa 3/26/2018 I am trying to put together a working configuration of Pycharm/Python/OpenCV for Windows 7 64 bit. I have read about the above software and have those versions. There is a lot (endless) literature on this subject but most is outdated and otherwise confusing with all the possible combinations. Apparently there are efforts to make this easy with the package managers. But, I cannot get past the error message ‘ImportError: DLL load failed: %1 is not a valid Win32 application’. Does anyone know the easy way?