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Found the solution

OpenCV: setting all pixels of specific BGR value to another BGR value

This was the open line solution of numpy fancy indexing with condition

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Used np.where

cim1 = cim.copy()
cim1[np.where((cim1==[49,51,31]).all(axis=2))]=[255,255,255]

I just took 0.13535053000123298 seconds